Direct Elimination Method Instructions (DE Method Series Part 2)

In part 1, we went over how using toxin binders in the rectum instead of orally can produce quick symptom relief, accelerate detox, spare your liver from stress, and give you your energy back. In this article, I will go over instructions for performing a toxin binder enema.

Direct Elimination Method Instructions:


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What binders do I use?

Binder selection is a nuanced subject that warrants its own article. I will discuss this in part 3 of the series. But the most important thing is that the binders be non-absorbable, so they can be introduced to the rectum and then excreted back out. Binders to avoid include things like cilantro which can be absorbed across the rectum into the blood, causing toxin redistribution. 

What water do I use?

The most important feature is that the water be clear of toxins such as chlorine compounds. In part 1, we went over how toxins can quickly diffuse out of the body’s blood supply and into the colon. This works the other way too. Toxins introduced into the colon can quickly diffuse into the blood through the iliac arteries and veins. 

You can use RO or distilled water, or spring water. If you have access to a hydrogen water machine such as Trusii, that is another good option. 

Which cup do I use?

For almost every situation, I prefer the small cups. You don’t need much water to get a toxin binder enema done. Plus they are great for traveling (yes, I will sometimes carry DE Method supplies with me when leaving the house in case of emergency toxin exposures). The lids are watertight as long as you screw them closed completely.

The only situation in which I use the larger Pyrex cup is when I need to use larger doses of binders, such as during a period of intense toxin mobilization. You will know this is happening when you find that you need to do many repeated enemas to get full symptom relief. Using more water and binders per enema saves time.



Now it’s time to detox! The basic idea is to mix binders with water and use this as an enema. But if you’ve never done an enema before, it can be helpful to have some more specific steps to guide you. You don’t have to do the DE method exactly like this, but these are the methods I’ve found helpful. I’ve included some photos using a cup with plain water to illustrate some more detailed points.

These steps can seem like a lot at first, but you’ll get the hang of them quickly. After several weeks of using the DE method every day I was able to perform an enema in under two minutes start to finish.

1. Find a good location for enemas

Ideally, you will be positioned so that you are squatting or have your legs forward. This aligns and straightens the rectum and colon (widens the anorectal angle), allowing for easier enema insertion. You can squat on a shower floor over an enema bucket, on a squat toilet, or a squatting stool that can be used with a regular toilet seat. Additionally, enemas can stimulate bowel movements. Be prepared for one to come out (have toilet paper on hand).

If you are not flexible or mobile enough to do a full squat, it will help to have your feet elevated and legs folded forward (knees raised up) while on the toilet. You can use a stool or short chair. 

2. Mix the enema

Pour a small amount of water into the cup. You shouldn’t need more than 4 oz of water unless you are intentionally going for a larger volume enema. Using less water makes the enema more comfortable and easier to hold for longer, so the binders can continue to filter toxins out of the blood. If you’re using the cups I provided a link to, fill the cup around halfway.

Measure the binders using the same measuring spoons, etc. as you would for taking them orally. In my and others’ experience, starting with half to one times as many the binders you would normally take orally is a good starting point. As you get experienced with the DE method you can start experimenting with what doses are best for you.

Add the binders to the water and mix with something like a stirring rod or spoon. You can use the handle of a measuring spoon, for example.

Personally, I often use the tip of the catheter to mix the binders in the water. This serves to lubricate the catheter too and allows you to skip step 3. This is best for ‘lighter’ binders that do not form a thick solution in water, such as activated charcoal powder or Microsilica. For ‘heavier’ or ‘stickier’ binders where the catheter is too flexible to mix them with water, I use the stem of the douche bulb. Examples of these ‘heavy’ binders include zeolite and grapefruit pectin.

3. Lubricate the catheter

Add a bit of the oil onto a small piece of paper towel and use it to lubricate the first inch or two of the catheter’s tip.

If you mix the binders in water with the catheter tip like I mentioned in step 2, then you can skip this step. As you get experienced with enemas, you’ll find it’s easier to insert the catheter with less or no lubrication.

4. Draw the enema into the douche bulb

Once your binders and water are mixed, it’s time to get them into the douche bulb. Squeeze the douche bulb with one hand to empty as much air as possible. With the other hand, tilt the cup with the enema solution diagonally. Point the stem of the douche bulb down so that the opening is pointing into the bottom-most corner of the tilted cup, held under the liquid surface. This position helps as much liquid as possible get sucked in.

Hold the cup and bulb in position while releasing pressure from the bulb, allowing it to fill. If positioned right, almost all (if not all) of the solution should go into the bulb.

5. Place the catheter firmly on the douche bulb stem

6. Slowly begin squeezing the bulb

The goal here is to get residual air out of the bulb, before squeezing into your rectum. Angle the bulb so the stem faces upwards. Squeeze the bulb until you see liquid starting to come into the catheter. While squeezing, hold the tip of the catheter with your other hand so it doesn’t flail around.

After you see liquid starting to come out, position the bulb so the stem angles downwards. This gets you ready to insert the catheter.  Hold the tip of the catheter steady with your other hand, in case liquid starts coming out.

7. Insert the catheter tip into the rectum

One to two inches (2.5-5 cm) is enough. You shouldn’t need to go more than several inches deep – don’t get too carried away.

For beginners this step is often the most difficult. If you are in a rush or are having difficulty, a shallow insertion is fine. The catheter just needs to be in far enough so that the liquid you’ll squeeze out actually goes into the rectum instead of spilling out.

8. Squeeze the enema liquid out of the bulb.

Be gentle. Your rectum will thank you.

When the bulb is almost empty, pay attention and start slowing down. There tends to be a bit of residual air in the bulb that gets squeezed out at the end. Once you see air coming into the catheter, back off and remove the catheter from your rectum. If there’s still a lot of liquid remaining in the bulb, you can repeat steps 6-8.

9. Hold the enema

Hold for as long as you keep feeling improvement in symptoms and are comfortable. Your body may want to excrete the enema almost immediately, or it may feel good holding onto it longer. Up to 30-40 minutes should be enough time.

10. Repeat if needed

You should feel noticeable symptom relief, within a few minutes of the enema. If you have a lot of toxins circulating, you may experience some relief but still have lingering symptoms. In this case, repeat these steps with another dose of the same binder, or using an enema of a different binder. For example, I have sometimes used four to five types of binders in a single session of enemas, as different binders have different affinities for various toxin types.

If you feel no benefit or worsening of symptoms, I will discuss potential reasons in part 4.

11. Replenish the colon

After you’re done with the toxin binder enemas, it’s good to replenish the rectum and colon with supplements such as trace minerals or probiotics. Sodium butyrate is a great supplement and nourishes colon cells, but be warned, it smells like sh*t (literally). Don’t use it if you have to go out and meet people afterwards.

Detox can be a draining process, requiring energy and nutrients. I find that adding in supplements like these help me feel even better after an enema session. 

12. Clean the douche bulb.

When you’re done with enemas, squeeze out any residual liquid into the toilet or enema bucket. Then rinse out the bulb to clean it. I just use clean water. I know some people who use agents like hydrogen peroxide for further disinfection, but I’ve found that my bulb has stayed clean with daily usage just rinsing with water after each session.

If you do clean with hydrogen peroxide or another agent make sure to fully rinse out any residues with clean water before your next enema session… I saw a Facebook post where someone had to go to the emergency department because they left their enema bulb filled with 35% hydrogen peroxide for cleaning and forgot to empty it out before using the bulb for more enemas. 


There you have it – how to perform a toxin binder enema and quickly relieve symptoms!

In part 3 I will go over how to choose what binders to use. In part 4 I will address safety concerns and troubleshooting.


14 Replies to “Direct Elimination Method Instructions (DE Method Series Part 2)”

    1. Hello John. I have seen clinicians mention that some people may see benefit from using regular CSM with the additives, as toxin removal may outweigh introduction of additives into the rectum. But given that this is a prescription medication I cannot provide any more individual advice and would suggest you discuss this with your healthcare provider.

    1. Rectally would be ideal

      Sorry for the late reply. I took some time away from blogging due to school responsibilities.

  1. In the section “Replenish the colon”, are you taking about taking those supplements by mouth or through another enema? Thanks and a great story! I’m definitely doing the DE method…maybe even tomorrow!

    1. Hi Mike,

      Rectal replenishment would be best so the nutrients are directly in contact with the colon cells. So you can mix the supplements into an enema

  2. Hi,

    I’ve just completed a Fecal Transplant so need to do everything I can to protect my new microbiome. Will this method harm the bacteria?

    Also, you mentioned in previous comments to replenish the colon via enema. Could this method also work for pre and pro biotics? I want to take both but I have SIBO so it creates difficulty in the small intestine.

    1. Hello! Enemas and colonics do have potential to disrupt the colonic microbiome. But then, toxins are also bad for the microbiome. Unless you are dealing with an acute toxic exposure it may be a good idea to hold off on this from now (this is just my opinion only, not medical advice).

      And yes, I have used probiotics rectally. I’m a fan of Megasporebiotic. Prebiotics I have never tried rectally.

  3. Hi Andrew, I just did my first rectal binder enema and it was pretty easy because I followed your instructions! Have you experimented with rectal suppositories or inserting capsules rectally? Is there an advantage to including water in the rectal binder?

    1. Hello Anita, the water allows the binders/supplements to be inserted more easily and evenly. Suppositories will also work (such as EDTA suppositories) but I do not recommend inserting supplements in standard gel pill capsules because those will not dissolve and be absorbed well.

  4. Hi Andrew.
    You’ve mentioned how quick this process can be…even 2 minutes. But you mention to hold it for 30-40 minutes while toxins are pulled out. Please clarify. With only 4 oz, is it usually easy to get up and move around while it’s working or does one need to stay in the bathroom in whatever position for that long?

    1. The amount of time to hold is variable, depending on the particular situation. Sometimes a few minutes may be enough, sometimes longer may be needed. If you want to get up and move around I would use a smaller amount of liquid like 1 or 2 oz

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